Dr. Ting Xie | Mechanics of Functional and Intelligent Materials | Materials Mechanics Industry Impact Award
Research Assistant at Peking Union Medical College Hospital | China
Dr. Xie Ting is a biomedical scientist whose interdisciplinary research spans molecular endocrinology, metabolic regulation, lipidomics, biobanking science, and translational physiology. She earned her doctoral training at the School of Biomedical Sciences of The Chinese University of Hong Kong, following advanced research work at the University of Chinese Academy of Sciences, Institute of Microbiology, and earlier foundational scientific training at The Central South Forestry University of Science and Technology. She has since contributed to the Peking Union Medical College Hospital Clinical Biobank, where she advances high-level clinical research through precision biospecimen science, multi-omics data generation, and mechanism-oriented disease exploration. Her scholarly contributions include extensive work on metabolic signaling and lipid biology, such as in Fibroblast Growth Factor 21 Protects Against Lipotoxicity-Induced Pancreatic β-Cell Dysfunction via Regulation of AMPK Signaling and Lipid Metabolism and Fibroblast Growth Factor 21: A Regulator of Metabolic Disease and Health Span, as well as innovative investigations in vascular pathology highlighted by Plasma Lipidomics Analysis Reveals the Potential Role of Lysophosphatidylcholines in Abdominal Aortic Aneurysm Progression and Formation and The Potential Role of Plasma Fibroblast Growth Factor 21 as a Diagnostic Biomarker for Abdominal Aortic Aneurysm Presence and Development. Her integrative cellular and molecular work extends further through studies such as Glucokinase Inactivation Ameliorates Lipid Accumulation and Exerts Favorable Effects on Lipid Metabolism in Hepatocytes, Integration of Proteomics and Metabolomics Reveals Energy and Metabolic Alterations Induced by Glucokinase Partial Inactivation in Hepatocytes, and The Relationship Between HIF1α and Clock Gene Expression in Patients with Obstructive Sleep Apnea. She has also contributed significantly to biobanking methodology through The Interference of RNA Preservative and Post-Collection Interval on RNA Integrity from Different Mice Tissues. Earlier in her career, she produced impactful enzymology and protein-engineering studies including Site-Saturation Mutagenesis of Central Tyrosine 195 Leading to Diverse Product Specificities of an α-Cyclodextrin Glycosyltransferase, Structural Basis of a Mutant Y195I α-Cyclodextrin Glycosyltransferase with Switched Product Specificity, and Increasing of Product Specificity of γ-Cyclodextrin by Mutating the Active Domain of α-Cyclodextrin Glucanotransferase. Through major national research fundings, invited presentations at global scientific congresses, and multiple academic honors, Dr. Xie Ting continues to advance the molecular understanding of metabolic disorders, vascular disease, endocrine biology, and clinical biobank innovation through publication-driven scientific excellence.
Featured Publications:
Genes Xie, T., Zhu, H., Wang, X., Li, F., Wang, A., Zhang, Y., Zhang, S., & Guo, D. (2025). The interference of RNA preservative and post-collection interval on RNA integrity from different mice tissues. Genes.
International Journal of Molecular Sciences Xie, T., Lei, C., Song, W., Wu, X., Wu, J., Li, F., Lv, Y., Chen, Y., Liu, B., & Zheng, Y. (2023). Plasma lipidomics analysis reveals the potential role of lysophosphatidylcholines in abdominal aortic aneurysm progression and formation. International Journal of Molecular Sciences, 24(12), 10253.
Nature and Science of Sleep Xie, T., Guo, D., Luo, J., Guo, Z., Zhang, S., Wang, A., Wang, X., Wang, X., Cao, W., Su, L., & others. (2022). The relationship between HIF1α and clock gene expression in patients with obstructive sleep apnea. Nature and Science of Sleep, 14, 381–392.