Prof. Dr. Yoon-Jin Lee | Bio-Mechanics | Research Excellence Award
Professor at Soonchunhyang University | South Korea
Prof. Dr. Yoon-Jin Lee is a distinguished faculty member in the Department of Biochemistry at Soonchunhyang University College of Medicine, recognized for her extensive contributions to cancer biology, metabolic regulation, and regenerative therapeutics. She earned her bachelorās, masterās, and doctoral degrees in Food and Nutrition from Soonchunhyang University, building a strong foundation in biochemical mechanisms, cellular metabolism, and nutraceutical science. Throughout her academic career as assistant professor, associate professor, and currently full professor, she has established herself as a leading researcher exploring how metabolic reprogramming shapes cancer cell survival, drug resistance, and cellular fate. Her research portfolio includes influential works such as āResveratrol Targets Glycolytic Enzymes HK II and PKM2 to Promote Concurrent Apoptotic and Necrotic Cell Death in Malignant Melanoma,ā āApoptosis, Cell Growth, and Glycogen Synthase Kinase 3Ī² Phosphorylation in Caffeic Acid-Treated Human Malignant Melanoma Cells,ā āCurcumin and Its Potential to Target the Glycolytic Behavior of Lactate-Acclimated Prostate Carcinoma Cells with Docetaxel,ā āMetabolic Reprogramming, Glycolysis Phenotype, Extracellular Vesicles, Prostate Cancer Cells,ā āEffect of Butein, a Plant Polyphenol, on Apoptosis and Necroptosis of Prostate Cancer Cells in 2D and 3D Cultures,ā and āEvaluating the Anticancer Potential of Polygonum Multiflori Root-Derived Stilbenes Against H2452 Malignant Pleural Mesothelioma Cells.ā Her interdisciplinary impact expands into neurobiology and regenerative medicine through works such as āEvaluation of Microcurrent as an Adjunct to Donepezil Therapy in an Alzheimerās Disease Mouse Model,ā āBioprinted Collagen Cell Constructs with Gradient BMP-2-Loaded Microbeads for Rotator Cuff Tear Regeneration,ā and āIn Vitro and In Vivo Comparative Analysis of Muscle Regenerative Processes Induced by Different Microcurrent Waveforms.ā Supported by multiple competitive national grants, Professor Lee continues to advance innovative therapeutic strategies targeting cancer metabolic pathways, bioactive natural compounds, microcurrent-based tissue repair, and the biochemical foundations of disease, positioning her as a leading contributor to modern biomedical research.
Featured Publications:
Lee, Y., Lee, S.-H., Choi, D., Nam, H.-S., Kim, K. D., Choi, M. H., Cho, M.-K., & Lee, Y.-J. (2025). Resveratrol targets glycolytic enzymes HK II and PKM2 to promote concurrent apoptotic and necrotic cell death in malignant melanoma. Current Issues in Molecular Biology.
Lee, Y.-J., Kim, K. D., Choi, M. H., Park, S. Q., Choi, Y. S., Bae, Y., Nam, H. S., Lee, S. H., & Cho, M. K. (2025). Apoptosis, cell growth, and glycogen synthase kinase 3Ī² phosphorylation in caffeic-acid-treated human malignant melanoma cells. Biomedicines.
Lee, Y.-J., Kwon, E. S., Moon, Y. S., & Kwon, D. R. (2025). In vitro and in vivo comparative analysis of muscle regenerative processes induced by different microcurrent waveforms in skeletal muscle atrophy. International Journal of Molecular Sciences.
Lee, Y.-J., Kwon, E. S., Moon, Y. S., & Kwon, D. R. (2025). In vitro and in vivo comparative analysis of muscle regenerative processes induced by different microcurrent waveforms in skeletal muscle atrophy [Preprint]. Preprints.
Lee, Y., Lee, C., Lee, S.-H., & Lee, Y.-J. (2025). Effect of butein, a plant polyphenol, on apoptosis and necroptosis of prostate cancer cells in 2D and 3D cultures. Life.